Thursday 2 August 2012

Week 9

Summary :
1. finished many-to-many mapping of Datanode Comparison results as mentioned in the last week's report. As you can see now in the screenshot below (in the table "Datanode Comparison Results"), some of the rows in the table have multiple datanodes in column Pathway1 and / or in  column Pathway2

In the results table, Bcl-Xs, BCL-XL in the column 'Pathway1' is mapped to BCL 2L 1 in Pathway2

2. Now there's an option to save the comparison results (as seen in the screenshot above) in a file. As you can see in the screenshot below, the "Save Comparison Results" button in the compare tab allows for saving the comparison results.

Clicking on the "Save Comparison Results" button saves the results in a text file. Right now the file's name and location are hard-coded. Might change this to allow the user to choose his/her preferred location and file name.
I am pasting below the text file's contents in which the results are saved.

<text file start>

Datanode Comparison Reuslts: to the left are Datanode-Labels in Pathway1 and to the right are their matching counterparts in Pathway2
----------------------------
TRADD, TRADD, TRADD <---> TRADD, TRADD
APAF1 <---> APAF1
C-IAP2 <---> BIRC3
p16-INK4 <---> CDKN2A
TNFR-2 <---> TNFRSF1B
AP-1, AP-1 <---> JUN
C-IAP1 <---> BIRC2
DFFB <---> DFFB
Bcl-Xs, BCL-XL <---> BCL2L1
CASP3 <---> CASP3
DR3, DR3 <---> TNFRSF25
Bim <---> BCL2L11
Noxa <---> PMAIP1
CASP9 <---> CASP9
CASP8, CASP8 <---> CASP8
IKB-alpha <---> NFKBIA, NFKBIA
CRADD <---> CRADD
TNFR-1, TNFR-1, TNFR-1 <---> TNFRSF1A, TNFRSF1A
TRAIL-R2 <---> TNFRSF10B
CASP6 <---> CASP6
Smac/DIABLO <---> DIABLO
c-FLIP, c-FLIP <---> CFLAR
DFFA <---> DFFA
BAK1 <---> BAK1
Cyto C <---> CYCS
Puma <---> BBC3
TRAF3 <---> TRAF3
MCL1 <---> MCL1
Nf-kB <---> NFKB1, NFKB1
FADD <---> FADD
BAX <---> BAX
FasL <---> FASLG
IKK <---> IKBKB
BAD <---> BAD, BAD
BCL2 <---> BCL2
BID <---> BID
CASP7 <---> CASP7
BOK <---> BOK
Survivin, survivin <---> BIRC5
FAS, FAS <---> FAS
CASP10 <---> CASP10
TRAIL <---> TNFSF10
Bcl-W <---> BCL2L2
HRK <---> HRK
CASP2 <---> CASP2

Interaction Comparison Reuslts: Datanodes are represented by their text-labels and MLine(<Line-style>) indicates that its a PathwayElement of type MLine
-------------------------------
FAS, MLine(0), FasL <---> FAS, MLine(0), FASLG
CASP8, MLine(0), BID <---> MLine(0), CASP8, BID
MLine(0), DFFB, DFFA <---> DFFB, MLine(0), DFFA

<text File end>

3. <Using Xref based lines in Interaction comaprison>
4. Scoring: <to be updated>

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